Purification and Characterization of Alkaline Phosphatase from Human Seminomas
スポンサーリンク
概要
- 論文の詳細を見る
Despite the apparent link between the presence of alkaline phosphatase (ALP) and various cancers, it has so far been difficult to determine distinct differences between seminoma-derived ALP and placental ALP (PLAP). In order to determine specificity, we purified ALP from a seminoma type of human testicular cancer tissue and compared its biochemical and immunological properties with those of PLAP. The purified ALP had a specific activity of 66 units per mg of protein, and it was possible to obtain 169 μg of purified preparation from 60 g of tissue. The molecular weight of the purified seminoma enzyme was approximately 500 kDa. We found that a novel type of ALP from human testicular cancer tissue exists, with a high molecular weight and differing in degree, from the seminoma ALP previously reported.
- 東海大学の論文
著者
-
Katsuoka Yoji
帝国臓器製薬
-
Katsuoka Yoji
Department Of Urology Osaka Medical College
-
Katsuoka Y
Department Of Urology Osaka Medical College
-
Katsuoka Yoji
Department Of Neurosurgery Osaka Medical College
-
YAMAMOTO Tateki
Natural Products Research Department, Teikoku Hormone Mfg. Co., Ltd.
-
Yamamoto T
Natural Products Research Department Teikoku Hormone Mfg. Co. Ltd.
-
Katsuoka Yoji
Department Of Internal Medicine Iii Osaka Medical College
関連論文
- A case of systemic lupus erythematosus with various central and pripheral neurological disorders developed with motor paralytic bladder as a major manifestation
- Expression and somatic mutation on androgen receptor gene in prostate cancer
- Prognostic significance of neuroendocrine differentiation, proliferation activity and androgen receptor expression in prostate cancer
- PJ-418 Effects of Chymase Inhibition on the Stenosis after Polytetrafluoroethylene Grafts Implantation(Restenosis, basic/clinical-5 (IHD) PJ71,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- The Effect of Chymase Inhibition on Arteriovenous Fistula Stenosis in Dogs (Peripheral Circulation/Vascular Disease 6 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Metastases to the penis from carcinoma of the prostate
- Marked Effect of Steroid-Resistant Focal Sclerotic Nephrotic Syndrome by Concomitant Therapy with LDL-Apheresis and Cyclosporine
- Telomerase activity in renal cell carcinoma by modified telomeric repeat amplification protocol assay
- Differently regulated androgen receptor transcriptional complex in prostate cancer compared with normal prostate
- Response of Tumors to Biologic Modifiers and Chemotherapeutic Agents
- Mechanisms of erythropoietin production in renal cell carcinoma
- Ultrastructural study on cytotoxic effects of cyclosporine A in spermiogenesis in rats
- Infiltration of H-2^d-Specific Cytotoxic Macrophage with Unique Morphology into Rejection Site of Allografted Meth A (H-2^d) Tumor Cells in C57BL/6 (H-2^b) Mice
- Influence of 15-deoxyspergualin on activated lymphocytes : Comparison of heart and renal rat transplantation models
- Management conditions during dialysis therapy influence the occurrence of complications after renal transplantation?
- BCG-Induced Enhancement of Tumor Growth in Experimental Bladder Tumor Model
- Basal cell carcinoma of the prostate : Report of a case and review of the published reports
- Embryonal carcinoma of the testis associated with prostate cancer in a 72-year-old man
- Ruptured cerebral aneurysm not detected by magnetic resonance angiography in juvenile autosomal domiant polycystic kidney
- A Case of Cryoglobulinemia with Precipitation at 35℃
- Purification and Characterization of Alkaline Phosphatase from Human Seminomas
- A successful conception by a shift from human menopausal gonadotropin therapy to therapy with recombinant human follicular-stimulating hormone for the treatment of male hypogonadotropic hypogonadism
- Basal cell carcinoma of the prostate : unusual subtype of prostatic carcinoma
- PARTIAL NEPHRECTOMY FOR RENAL CELL CARCINOMA IN A SOLITARY KIDNEY