BCG-Induced Enhancement of Tumor Growth in Experimental Bladder Tumor Model
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概要
- 論文の詳細を見る
Transitional-cell carcinoma of the bladder has been induced by chronic oral administration of N-(4-(5-nitro-2-furyl)-2 thiazolyl) formamide (FANFT) in C3H/He mice, and successfully transplanted in syngeneic animals. Treatment was attempted under 2 major categories, namely, by preimmunization with tumor antigens or BCG, and by BCG administration through different routes. Classic tumor challenge experiments showed the presence of tumor associated antigens on FANFT tumor cells. In this present study, BCG treatment promoted rather than inhibited the growth of FANFT tumor. Some proposed explanations for mechanism (s) of tumor enhancement following BCG immunostimulation were discussed.
- 東海大学の論文
著者
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Katsuoka Yoji
Department Of Urology Osaka Medical College
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Katsuoka Yoji
Department Of Neurosurgery Osaka Medical College
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Katsuoka Yoji
Department Of Urology School Of Medicine Tulane University:department Of Urology School Of Medicine
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deKERNION Jean
Veterans Administration Hospital of New Orleans
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Katsuoka Yoji
Department Of Internal Medicine Iii Osaka Medical College
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