Release and Rectal Absorption of Aminophylline Suppositories Prepared in a Hospital Pharmacy

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概要

• 論文の詳細を見る

• In vitro release and in vivo rectal absorption of suppositories containing aminophylline and various bases prepared in our hospital pharmacy were investigated. The release tests were conducted using three methods: the cylindrical filter paper method, the Sartorius solubility simulator method and the disintegration test in J. P. IX. In all cases, release from PEG-containing suppositories was better than that from Witepsol-containing products. However, this tendency was not reflected in the blood level of theophylline after rectal absorption of these suppositories.

• 東海大学の論文

著者

• KUBOTA Akie

  Department of Pharmacy, Tokai University Hospital

• MIZUSHIMA Noriko

  Department of Pharmacy, Tokai University Hospital

• Kubota Akie

  Department Of Pharmacy Tokai University Hospital

• Fujii Tadao

  Department Of Pharmacy Tokai University Hospital

• Mizushima Noriko

  Department Of Pharmacy Tokai University Hospital

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