A Successful Running Wheel Method of Active Avoidance Learning for 240 Minutes on Fisher-strain Rats

概要

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Active avoidance learning using a running wheel method was performed on Fisher-strain rats. Iso et al. reported that Fisher-strain rat was the most excellent animal on the ability of learning. By the usual psychological method, avoidance learning can be successful after 7 to 14 days trials against task. In this paper, the authors developed a simple method of learning which requires only short learning period (4 hours in total). Three experiments were performed in the following manner. On experiment 1, learning trials were performed to the animals every 24 hours. A learning trial consisted of three 10-minute running periods with two 5-minute rests (40 minutes total). On experiment 2, the interval between trials was 60 min. In these 2 experiments, the number of shocks was reduced significantly. However, significant decrease of the number of shocks was not obtained on experiment 3: intervals between the trials were 10 min. For successful learning, intervals between trials may have to be long enough for the rats to recover from panic-like situation.
神戸大学の論文
1997-01-24