Effects of Shock Waves on Living Tissue Cells and its Deformation Process Using a Mathematical Model

概要

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In this study, damage of living tissue cells (red blood cells and cancer cells) and experimental cell models (microcapsules) by plane shock waves is carried out experimentally. In addition, the effects of physical condition on the degree of damage are evaluated by constructing an appropriate mathematical model. To explain these phenomena, the red blood cells and the microcapsules are modeled mathematically as two spherical elastic shells filled with liquid. The fundamental equations express the oscillation of the spherical elastic shell in response to the incident pressure wave in the surrounding fluid. Frequency responses of the elastic shell model of two living tissue cells with mutual interaction in water are analyzed. From the results of this analysis, the effects of (1) the rise time of shock waves, (2) the distance between cells on shock-induced damage, (3) the concentration of suspended cells and (4) the incideuce angle of shock waves are discussed. It is found that effects of these parameters are large in certain cases.
一般社団法人日本機械学会の論文
1999-09-15