Heat-killed Propionibacterium Acnes Up-regulates Toll-like Receptor 4 on Macrophages
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概要
- 論文の詳細を見る
"It is known that heat-killed Propionibacterium acnes (P.acnes) induces lipopolysaccharide (LPS) hypersensitivity. However, effect of the P.acnes on expression of Toll-like receptor (TLR) 4 remains unclear. To determine whether or not TLR4 expression of macrophages can be changed by the P.acnes stimulation, TLR4 of RAW264.7 cells as measured after the P.acnes stimulation in vitro. Furthermore, the P.acnes-treated mice were measured as to the expression of TLR4 mRNA in the liver. The P.acnes treatment increased the TLR4 expression on RAW264.7 cells. The P.acnes-treated mice also were expressed as TLR4 mRNA in the liver. These results may suggest that an up-regulation of TLR4 on macrophages can be induced by heat-killed P.acnes treatment."
- 川崎医療福祉大学の論文
著者
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Yano Hiromi
Kawasaki University Of Medical Welfare
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Shiva Daisuke
Kawasaki University Of Medical Welfare
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Shiva Daisuke
Division Of Health Science Kawasaki University Of Medical Welfare
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"Shiva Daisuke
"Doctoral Program in Health Science, Graduate School of Health Science and Technology, Kawasaki Univ
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Matsumoto Takashi
Master's Program in Health and Sports Science, Graduate School of Health Science and Technology, Kaw
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Yano Hiromi"
Department of Health and Sports Science, Faculty of Health Science and Technology, Kawasaki Universi
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Matsumoto Takashi
Microbiology Department Of Infectious Disease Faculty Of Medicine Oita University
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