A New Cytotoxic Daphnane Diterpenoid, Rediocide G, from Trigonostemon reidioides

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概要

• 論文の詳細を見る

• Rediocide G (7), a new daphnane diterpenoid, was isolated from the roots of Trigonostemon reidioides (Euphorbiaceae), together with two congeners, rediocide A and rediocide B, (+)-syringaresinol, scopoletin, tomentin and stigmasterol. The structure of the new natural product was elucidated by comparison of its NMR and mass spectral data with those of previously known rediocides and confirmed by extensive 2D NMR spectral analysis. Rediocide G (7) was found to be cytotoxic to various cancer cell lines.

• 公益社団法人日本薬学会の論文
• 2005-10-01

著者

• Thasana Nopporn

  Chulabhorn Res. Inst. Vipavadee Rangsit Highway

• Ruchirawat Somsak

  Institute Of Science And Technology For Research And Development Mahidol University:laboratory Of Me

• Siripong Pongpun

  Natural Product Research Section Research Division National Cancer Institute

• Chuakul Wongsatit

  Department Of Pharmaceutical Botany Faculty Of Pharmacy Mahidol University

• TEMPEAM Atchara

  Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University

• THASANA Nopporn

  Laboratory of Medicinal Chemistry, Chulabhorn Research Institute

• PAVARO Chitkavee

  Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University

• Tempeam Atchara

  Department Of Pharmaceutical Chemistry Faculty Of Pharmacy Mahidol University:institute Of Science A

• Pavaro Chitkavee

  Department Of Pharmaceutical Chemistry Faculty Of Pharmacy Mahidol University

関連論文

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• Acaricidal Daphnane Diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots
• Variation in growth and diterpene lactones among field-cultivated Andrographis paniculata
• Antitumor Activity of Liposomal Naphthoquinone Esters Isolated from Thai Medicinal Plant : Rhinacanthus nasutus KURZ.(Biopharmacy)
• Induction of Apoptosis in Tumor Cells by Three Naphthoquinone Esters Isolated from Thai Medicinal Plant : Rhinacanthus nasutus KURZ(Pharmacognosy)
• Antiproliferative naphthoquinone esters from Rhinacanthus nasutus Kurz. roots on various cancer cells
• COX-1, COX-2 Inhibitors and Antifungal Agents from Croton hutchinsonianus
• Induction of Apoptosis by Rhinacanthone Isolated from Rhinacanthus nasutus Roots in Human Cervical Carcinoma Cells
• A New Cytotoxic Daphnane Diterpenoid, Rediocide G, from Trigonostemon reidioides
• Inhibitory Effect of Liposomal Rhinacanthin-N Isolated from Rhinacanthus nasutus on Pulmonary Metastasis in Mice

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