Vibrational Test for Evaluation of Creams. I. The Effect of Vertical Vibration Imposed on O/W Creams

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概要

• 論文の詳細を見る

• The steady flow behavior, dynamic characteristics and particle size (microscopical counting) of a semisolid O/W cream prepared with cetomacrogol and cetostearyl alcohol were studied. The continuous shear flow curve of this cream was in the form of an anti-clockwise hysteresis loop. Vertical vibration imposed on the cream, using a Sanki viscoelasto recorder, caused a first-order breakdown of viscoelastic structure formed in the cream at a rate of 10^<-5> s^<-1> for dynamic viscosity and 10^<-4> s^<-1> for dynamic modulus, while the vibration caused coalescence of the oil globules dispersed in the cream at a rate of 10^<-15> s^<-1>. The destruction of viscoelastic structure was much more rapid than the coalescence.

• 公益社団法人日本薬学会の論文
• 1984-07-25

著者

• 黒田 稔

  Pharmaceutical Formulation Research Center, Research Institute, Daiichi Seiyaku Co., Ltd.,

• 黒田 稔

  Otc Research Group Research Institute Daiichi Pharmaceutical Co. Ltd.

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• Vibrational Test for Evaluation of Creams. I. The Effect of Vertical Vibration Imposed on O/W Creams

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