Nitric Oxide and Immune Complexes Are Involved in the Induction of a Novel Luminol Chemiluminescencwe in Cytotoxic Macrophages
スポンサーリンク
概要
- 論文の詳細を見る
A chemiluminescence (CL) was observed immediately after the addition of luminol to thioglycollate-elicited ICR mouse peritoneal macrophages (Mφ) that had been incubated overnight with recombinant murine interferon-γ(IFN-γ) and lipopolysaccharides (LPS). The intensity of this CL was closely correlated with the cytotoxic activity of Mφ. N^G-minomethyl-L-arginine (L-NMMA), an inhibitor of nitric oxide (NO) synthase, inhibited the induction of this CL, and L-arginine restored the L-NMMA-induced inhibition. These results suggest that NO is directly involved in the induction of CL. However, we found that immune complexes are required for the induction of CL as well as NO.
- 公益社団法人日本薬学会の論文
- 1996-11-15
著者
-
Yuki Hidetaka
Department Of Clinical Chemistry School Of Pharmaceutical Sciences Toho University
-
Matsumoto Kojiro
Department Of Clinical Chemistry Faculty Of Pharmaceutical Sciences Toho University
-
MUTO Satoshi
Department of Clinical Chemistry, School of Pharmaceutical Sciences, Toho University
-
SUMI Kaori
Department of Clinical Chemistry, School of Pharmaceutical Sciences, Toho University
-
INAGE Yumiko
Department of Clinical Chemistry, School of Pharmaceutical Sciences, Toho University
-
Sumi Kaori
Department Of Clinical Chemistry School Of Pharmaceutical Sciences Toho University
-
Muto Satoshi
Department Of Clinical Chemistry School Of Pharmaceutical Sciences Toho University
-
Inage Yumiko
Department Of Clinical Chemistry School Of Pharmaceutical Sciences Toho University
関連論文
- Binding Affinities of NKG2D and CD94 to Sialyl Lewis X-Expressing N-Glycans and Heparin
- Glycated Human Serum Albumin Induces Interleukin 8 mRNA Expression through Reactive Oxygen Species and NADPH Oxidase-Dependent Pathway in Monocyte-Derived U937 Cells(Biochemistry)
- Development of an Enzyme-Linked Immunosorbent Assay System to Determine the Presence of Antibodies Specific for Taxane Structures
- Natural Killer Group 2A (NKG2A) and Natural Killer Group 2C (NKG2C) Bind to Sulfated Glycans and α2,3-NeuAc-containing Glycoproteins
- Protein O-N-Acetylglucosaminylation Modulates Promoter Activities of Cyclic AMP Response Element and Activator Protein 1 and Enhances E-Selectin Expression on HuH-7 Human Hepatoma Cells(Molecular and Cell Biology)
- Enhanced Expression of Membrane-Associated Sialidase Neu3 Decreases GD3 and Increases GM3 on the Surface of Jurkat Cells during Etoposide-Induced Apoptosis(Molecular and Cell Biology)
- Increased Expression of Lewis X and Y Antigens on the Cell Surface and FUT 4 mRNA during Granzyme B-Induced Jurkat Cell Apoptosis(Molecular and Cell Biology)
- NF кB-p65 Dependent Transcriptional Regulation of Glycosyltransferases in Human Colon Adenocarcinoma HT-29 by Stimulation with Tumor Necrosis Factor α(Highlighted paper selected by Editor-in-chief,Biochemistry)
- Targeted Proteo-Glycomics Analysis of Sialyl Lewis X Antigen Expressing Glycoproteins Secreted by Human Hepatoma Cell Line
- A Fluorometric Assay for Glycosyltransferase Activities Using Sugars Aminated and Tagged with 7-Hydroxycoumarin-3-carboxylic Acid as Substrates and High Performance Liquid Chromatography
- Nitric Oxide and Immune Complexes Are Involved in the Induction of a Novel Luminol Chemiluminescencwe in Cytotoxic Macrophages
- Human Mannose-Binding Lectin Preferentially Binds to Human Colon Adenocarcinoma Cell Lines Expressing High Amount of Lewis A and Lewis B Antigens
- Alterations in Cell Surface Phosphatidylserine and Sugar Chains during Apoptosis and Their Time-Dependent Role in Phagocytosis by Macrophages(Biochemistry/Molecular Biology)
- Unlike Natural Killer (NK) p30, Natural Cytotoxicity Receptor NKp44 Binds to Multimeric α2,3-NeuNAc-Containing N-Glycans
- Decreases in CD31 and CD47 Levels on the Cell Surface during Etoposide-Induced Jurkat Cell Apoptosis
- PREDICTION OF RECURRENCE FOR NON-SMALL CELL LUNG CANCER BY COMBINED ANALYSIS OF MOLECULAR MARKERS AND 18F 2-FLUORO-2-DEOXY-D-GLUCOSE POSITRON EMISSION TOMOGRAPHY