Carbonic Anhydrase Activators. VII. Isozyme II Activation by Bisazolyl-methanes, -ethanes and Related Azoles

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概要

• 論文の詳細を見る

• A correlation was found between the carbonic anhydrase II activating power and the pK_a values for a series of azoles, bisazolylmethanes and bisazolylethanes. Strong activations were found for compounds with pK_a's in the interval 6.5-8.0. The mechanism of action for such activators is discussed.

• 社団法人日本薬学会の論文
• 1993-12-15

著者

• Claramunt R

  Departamento De Quimica Organica Y Biologia

• Claramunt R

  Uned Madrid Esp

• CLARAMUNT Rosa

  Departamento de Quimica Organica y Biologia

• LAVANDERA Jose

  Departamento de Quimica Organica y Biologia

• ELGUERO Jose

  Instituto de Quimica Medica, CSIC

• CABILDO Pilar

  Departmento de Quimica Organica y Biologia, Facultad de Ciencias, UNED & CSIC, Ciudad Universitaria

• SUPURAN Claudiu

  University of Bucharest

• BALABAN Alexandru

  Department of Chemistry, Bd. Carol I (Republicii) 13, 70346 Bucharest, Roumania, Polytechnic Univers

• Elguero J

  C.s.i.c. Madrid Esp

• Elguero Jose

  Instituto De Quimica Medica Csic

• Elguero Jose

  ウルグアイ

• Elguero Jose

  Instituto De Quimica Medica

• Cabildo P

  Uned Madrid Esp

• Supuran Claudiu

  Universita Degli Studi

• Balaban Alexandru

  Department Of Chemistry Bd. Carol I (republicii) 13 70346 Bucharest Roumania Polytechnic University

• Cabildo Pilar

  Departmento De Quimica Organica Y Biologia Facultad De Ciencias Uned & Csic Ciudad Universitaria

関連論文

• Carbonic Anhydrase Activators. XV. A Kinetic Study of the Interaction of Bovine Isozyme II with Pyrazoles, Bis- and Tris-azolyl-methanse
• Synthesis of 3-(1-Adamantyl)pyrazole and 3,5-Di(1-adamantyl)pyrazole in a Microwave Oven
• Carbonic Anhydrase Activators. VII. Isozyme II Activation by Bisazolyl-methanes, -ethanes and Related Azoles
• Binuclear Pyrazoles. I. Synthesis and Cytotoxic Activity of 1,1'-Dibenzyl and 1,1'-Dihydroxymethyl 4,4'-Bispyrazoles
• Research for New Antichagasic Drugs
• Synthesis and Antifungal Properties of Some N, N'-Bis-azolylarylmethanes
• Aromatic systems with 10.PI. electrons derived from 3a-azapentalene. Part 40. Studies on the 1,2,4-triazolo(4,3-b)(1,2,4)triazole series.

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