Synthesis and Antifungal Properties of Some N, N'-Bis-azolylarylmethanes

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概要

• 論文の詳細を見る

• A series of 1,1'-bis-azolylarylmethanes has been prepared by reaction of azoles and their benzoderivatives with ortho-, and para-chlorobenzaldehydes, thiophene-2-carbaldehyde and furan-2-carbaldehyde in the presence of zinc chloride as catalyst. The antifungal activity has been tested, in vitro, against Botrytis cinerea, Aspergillus flavus, Mucor rouxii and Candida albicans. All 1,1'-bis-azolylarylmethanes have minima inhibitory concentrations (MIC) higher than that of chlotrimazol, used as positive control.

• 公益社団法人日本薬学会の論文
• 1988-06-25

著者

• Claramunt R

  Departamento De Quimica Organica Y Biologia

• Claramunt R

  Uned Madrid Esp

• Elguero Jose

  Insto. Quimica Medica Csic

• Gomez-alarcon Gonzalo

  Centro De Investigaciones Biologicas Csic

• CLARAMUNT Rosa

  Dpto. Quimica Organica, Facultad de Ciencias

• BALLESTEROS PALOMA

  Dpto. Quimica Organica, UNED

• LOPEZ M.CARMEN

  Dpto. Quimica Organica, UNED

• Lopez M.carmen

  Dpto. Quimica Organica Uned

• Ballesteros Paloma

  Dpto. Quimica Organica Uned

• Claramunt Rosa

  Dpto. Quimica Organica Facultad De Ciencias

関連論文

• Carbonic Anhydrase Activators. XV. A Kinetic Study of the Interaction of Bovine Isozyme II with Pyrazoles, Bis- and Tris-azolyl-methanse
• Synthesis of 3-(1-Adamantyl)pyrazole and 3,5-Di(1-adamantyl)pyrazole in a Microwave Oven
• Carbonic Anhydrase Activators. VII. Isozyme II Activation by Bisazolyl-methanes, -ethanes and Related Azoles
• Research for New Antichagasic Drugs
• Synthesis and Antifungal Properties of Some N, N'-Bis-azolylarylmethanes

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