立体化学の研究(第10報)dl-フェニルセリノール類 : その新合成法と立体化学的知見(3)塩基性媒剤に於けるdl-threo-2-Phenyl-4-phenylhydroxymethyl-⊿^2-oxazolineの開環
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概要
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The treatment of dl-threo-1-phenyl-1-benzoyloxy-2-amino-3-bromopropane (I) hydrobromide in basic media yielded dl-1-phenyl-2-benzoylaminoprop-1-en-3-ol (or dl-1-phenyl-2-benzoyliminopropan-3-ol) (IV) via dl-threo-2-phenyl-4-phenylhydroxymethyl-⊿^2-oxazoline (II). dl-threo-1-Phenyl-2-benzoylaminopropane-1,3-diol (III) was also formed by treatment of hydrobromide of (I) with potassium acetate and hydrous ethanol. These formation mechanisms were discussed on the ground of stereochemical findings.
- 公益社団法人日本薬学会の論文
- 1956-12-20
著者
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友枝 宗光
Eisai Co., Ltd.
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友枝 宗光
Eisai Co. Ltd.
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田口 胤三
Pharmaceutical Institute, Medical Faculty, University of Kyushu
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友枝 宗光
Pharmaceutical Institute, Medical Faculty, University of Kyushu
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田口 胤三
Pharmaceutical Institute Medical Faculty University Of Kyushu
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