立体化学の研究(第4報)アルカノールアミン(4)dl-Regular-2,5-Diphenyl-4-methyloxazoline : その生成とMethyl Tosylateの作用

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Of the two forms of dl-2,5-diphenyl-4-methyloxazolines, the ψ-form has been obtained, but not the regular form. Therefore, the formation of the latter was studied and was successfully obtained by two ways, the one being based on the reaction between dl-norephedrine and benzimidoethyl ether hydrochloride, and the other on the treatment of dl-ψ-1-phenyl-1-chloro-2-benzoylaminopropane with boiling absolute ethanol containing anhydrous sodium carbonate. Further, the regular oxazoline was reacted with methyl tosylate and yielded dl-O-benzoylephedrine tosylate. The purpose of the reaction was to find and example of the new method of N-monoalkylation of β-amono-alcohols, which was reported in the previous papers.^<1,3,4)>
公益社団法人日本薬学会の論文
1955-02-20