Synthesis of Nereistoxin and Related Compounds. II

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概要

• 論文の詳細を見る

• An improved synthesis of nereistoxin (VII or XIII ; R_3=CH_3) was achieved via the intermediates VIII (R_3=CH_3), X (R_3=CH_3) and XII (R_3=CH_3) as summarized in Chart 2. Applying the reactions formulated in Chart 1 and Chart 2,a number of amines were prepared, whereby the occurrence of intermediates, cyclic sulfonium (III) in the amination reaction in Chart 1 and cyclic immonium (IX) in the thiolation reaction in Chart 2 respectively, was suggested.

• 社団法人日本薬学会の論文
• 1968-02-25

著者

• 沼田 光雄

  Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

• 沼田 光雄

  Medicinal Research Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 沼田 光雄

  Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.

• (故)萩原 彦一

  Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

• (故)萩原 彦一

  Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.

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• Synthesis of Nereistoxin and Related Compounds. II

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