茵〓蒿の研究(第1報) : 新利胆成分Capillarisin
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概要
- 論文の詳細を見る
A new choleretic substance, capillarisin (I), was isolated from the herb of Artemisia capillaris Thunb. (Japanese name, "Inchinko"茵〓蒿) by tracing the activity in rats. By heating with 1% NaOH or H_2SO_4 in methanol, I was cleaved to p-hydroquinone and a compound (XI) or p-hydroquinone and the compound (XII). Infrared and ultraviolet spectra suggested that I and XI are chromone derivatives and XII is a coumarin derivative. Positions of the functional groups in XI and XII were determined by direct comparison with the synthetic samples, and the structure of I was established as 2-(p-hydroxy-phenoxy)-6-methoxy-5,7-dihydroxychromone.
- 公益社団法人日本薬学会の論文
- 1976-07-25
著者
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小宮 威彌
武田薬品工業株式会社中央研究所生薬研究所
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津久井 誠
武田薬品工業株式会社中央研究所京都試験農園
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小宮 威彌
Central Research Division Takeda Chemical Industries Ltd.
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大塩 春治
武田薬品工業株式会社 中央研究所 生薬研究所
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大塩 春治
Pharmacognostic Research Laboratory Takeda Chemical Industries Ltd.
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津久井 誠
Pharmacognostic Research Laboratory Takeda Chemical Industries Ltd.
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