アズレンに関する研究(第7報)グアイアズレンに対する塩化プロピルの作用

概要

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The compounds produced by the action of propyl or isopropyl chloride with guaiazulene had been comfirmed as the 3-substituted derivatives of guaiazulene from the visible region and nuclear magnetic resonance spectra. In the reaction with iso-propyl chloride, only one product (I) was obtained, but two products were produced from the reaction with propyl chloride. One of the two latter products was identified with I from retention time and mixed melting point test of the trinitrobenzoate. I and the other (II) were separated from the latter products by gas chromatography and both compounds were examined by mass and nuclear magnetic resonance spectra. From these results, it was confirmed that I and II correspond respectively to 3-isopropyl- and 3-propyl-guaiazulene.
公益社団法人日本薬学会の論文
1971-06-25