新規アクリジン誘導体のトポイソメラーゼII依存性DNA鎖切断活性とマウス白血病P388抗がん活性
スポンサーリンク
概要
- 論文の詳細を見る
In order to clarify the mechanism of topoisomerase II mediated DNA cleavage activity caused by intercalators (9-anilinoacridines), antitumor activities against murine P388 and calf thymus DNA topoisomerase II mediated DNA cleavage activities of compounds m-AMSA, A4P73,A3P56,and A3P166 have been studied. A4P73 was found to have potent antitumor and DNA cleavage activities.
- 社団法人日本薬学会の論文
- 1994-05-25
著者
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木邑 道夫
京都大学医学部附属病院
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木邑 道夫
Department Of Pharmacy Kyoto University Hospital Faculty Of Medicine Kyoto University
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