療品の放射線殺菌II : 腸腺縫合糸におよぼす放射線照射の影響

概要

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Catguts (Type A and Type C, size, 2-0) sealed into various solution were used in this experiment. The tensile strength of the guts decreased with increasing dose, but the decreasing degree of strength by irradiation at sterilizing dose 2.5 Mrad showed less than 10%. No significant difference was observed in the tensile strength between the guts irradiated after sealing into isopropyl alcohol, xylene or toluene, and the guts sealed into isopropyl alcohol after irradiating in dry state. Absorbency of the irradiated guts was examined by measuring the tensile strength after the im mersion in artificial gastric juice or rabbit serum in the comparison with the non-irradiated guts. There was found no difference of the tensile strength between irradiated and nonirradiated guts. The sterilizing dose was determined by using the guts and the paper contaminated with Bacillis subtilis PCI219 spores. Even the samples contaminated with 10^6-10^7 spores were sterilized at a dose level of 2.5 Mrad. Decreasing radioresistance of the spores was observed with increasing time immersed in isopropyl alcohol.
公益社団法人日本薬学会の論文
1967-10-30