Microbial Degradation of Chlorhexidine by Clinical Isolates
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概要
- 論文の詳細を見る
Chlorhexidine degradation by clinical isolates such as Pseudomonas aeruginosa, Pseudomonas cepacia, Alcaligenes faecalis, Alcaligenes xylosoxidans, Serratia marcescens and Pseudomonas sp. strain No. A-3 (as a control organism) was investigated after enrichment with chlorhexidine. By this enrichment, P. aeruginosa (Nos. 1-3), A. faecalis, A. xylosoxidans (No.2) and S. marcescens IFO 3046 smoothly acquired resistance to a high concentration of chlorhexidine. Among them, only S. marcescens IFO 3046 showed the same degradation pattern as the control organism, which degraded chlorhexidine via a modified degradation pathway. The other strains were thought to have a different resistance system from that of Pseudomonas sp. strain No. A-3 and S. marcescens IFO 3046.
- 社団法人日本薬学会の論文
- 1996-08-31
著者
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上田 勝
Faculty of Pharmaceutical Sciences Kumamoto University
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塩崎 妙子
Faculty of Pharmaceutical Sciences Kumamoto University
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横溝 和美
Faculty of Pharmaceutical Sciences Kumamoto University
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鈴木 啓太郎
Faculty of Pharmaceutical Sciences Kumamoto University
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上田 勝
熊本大学 薬
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渡邉 啓太
Faculty Of Pharmaceutical Sciences Kumamoto University
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榎田 孝子
Faculty of Pharmaceutical Sciences, Kumamoto University
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小宮 香織
Faculty of Pharmaceutical Sciences, Kumamoto University
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榎田 孝子
Faculty Of Pharmaceutical Sciences Kumamoto University
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小宮 香織
Faculty Of Pharmaceutical Sciences Kumamoto University
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