Changes in Middle Latency Auditory-Evoked Potentials of the Rat Exposed to Styrene
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概要
- 論文の詳細を見る
Effects of styrene exposure on middle latency auditory-evoked potentials (MAEPs), which reflect the central auditory function, were investigated. As significant delay in latencies of No, Po, Na, and Pa components and increases in the peak to peak intervals of MAEPs, but not amplitudes, were observed in a dose-dependent manner. The present and our previous studies demonstrate that electrophysiological alterations occur before neuronal cell damage induced by styrene exposure. The present results suggested that styrene has a marked effect on the processing of auditory information related to MAEPs.
- 公益社団法人日本薬学会の論文
- 2001-04-01
著者
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KURASAKI Masaaki
Department of Environmental Medicine and Informatics, Graduate School of Environmental Earth Science
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Wang Yu-ping
Laboratory Of Environmental Biology Hokkaido University School Of Medicine
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SAITO Takeshi
Laboratory of Environmental Biology, Hokkaido University School of Medicine
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Hosokawa Toshiyuki
Center for Research and Development in Higher Education, Hokkaido University
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Saito Kazuo
Laboratory of Environmental Biology, Hokkaido University School of Medicine
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Hosokawa Toshiyuki
Research Division For Higher Education Center For Research And Development In Higher Education Hokka
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Kurasaki Masaaki
Department Of Environmental Medicine And Imformatics Hokkaido University
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Sakoda K
Laboratory Of Environmental Biology Hokkaido University School Of Medicine
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Saito Koichi
Sumitomo Chemical Co. Ltd.
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Saito Kazuo
Laboratory Of Environmental Biology Hokkaido University School Of Medicine
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Saito Takeshi
Laboratory Of Environmental Biology Hokkaido University School Of Medicine
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