Preparation of a Monoclonal Antibody Specific for Human Stanniocalcin
スポンサーリンク
概要
- 論文の詳細を見る
Stanniocalcin (STC) is a glycoprotein hormone that was first identified in fish, where it regulates the calcium level in the body fluid. The cDNA which encodes human STC has recently been reported but the function has not been completely elucidated. We have prepared a monoclonal antibody against human STC using an analogous peptide of the putative antigenic domain in human STC; it was conjugated with keyhole limpet hemocyanin (KLH). The monoclonal antibody specifically stained the distal convoluted tubules in human kidney which is a putative target organ of STC. The ELISA was established using the monoclonal antibody and recombinant human STC as a standard antigen. The monoclonal antibody prepared in this study provides a useful tool for clinical studies of STC in human.
- 公益社団法人日本薬学会の論文
- 1998-12-15
著者
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Sasaki Takeshi
Department of Rheumatology, Tohoku University school of Medicine
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KOIDE YOSHIO
Department of Molecular Diagnostics, Tohoku University Graduate School of Medicine
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佐々木 毅
東北大学大学院医学系研究科免疫血液病学分野
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SATO KANAKO
Department of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital
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Takano Shoichi
R & D Center Bml Inc.
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Sasaki Takeshi
Department Of Biotechnology College Of Agriculture Ehime University
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Sato Kanako
Department Of Anesthesiology And Pain Relief Center The University Of Tokyo Hospital
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Sato Kanako
Department Of Clinical And Laboratory Medicine Tohoku University School Of Medicine
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IGARASHI Akira
R & D Center, BML, Inc.,
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SAKUMA Nobuhiro
Department of Clinical and Laboratory Medicine, Tohoku University, School of Medicine
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SHIBATA Shinobu
The Second Department of Internal Medicine, Tohoku University, School of Medicine
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TADA Kotaro
Department of Immunology, Tohoku University, School of Medicine
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TAKANO Shoichi
R & D Center, BML, Inc.,
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Tada Kotaro
Department Of Immunology Tohoku University School Of Medicine
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Shibata S
The Second Department Of Internal Medicine Tohoku University School Of Medicine
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Sakuma Nobuhiro
Department Of Clinical And Laboratory Medicine Tohoku University School Of Medicine
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Igarashi A
Fukushima Medical Univ. Hospital Fukushima Jpn
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Koide Yoshio
Department Of Clinical And Laboratory Medicine Tohoku University School Of Medicine
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Koide Yoshio
Department Of Applied Mathematics Faculty Of Engineering Science Osaka University
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Sasaki Takeshi
Department Of Clinical And Laboratory Medicine Tohoku University School Of Medicine
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Sasaki Takeshi
Department Of Agricultural Chemistry Faculty Of Agriculture Ehime University
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