Exhalation Behavior of Four Organic Substrates and Water Absorbed by Human Skin
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概要
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The simultaneous measurement of several volatile organic compounds and water released from the human skin can be achieved successfully by using a modified gas chromatographic system. After the thumb of each subject was dipped in aqueous solution containing acetone, diethyl ether, ethanol, and toluene, it was dried in the air. Then the thumb attached to the sampling probe for measuring the released gases. It is found that 90% of all these chemical substrates were desorbed after 20 mim. The initial exhalation rate factor for each chemical substrate was determined in every subject. Correlation factors of the linear relationships between the initial exhalation rate for hydrophilic substrates (acetone and ethanol) and the total amount of water (TAW) released from the skin were 0.94 and 0.92, respectively. However, the rate of hydrophobic toluene was not dependent on the TAW. Therefore, the exhalation rate of substrates is greatly influenced by both their hydrophilicity and TAW. Additionally, an interesting personal specific character among the 6 subjects was observed on plotting the exhalation rate of organic substrates and water during the elapsed time. With the released water mostly due to insensible perspiration, the exhalation rate of all simultaneous organic substrates decreased monotonically over the elapsed time. On the contrary, when subjects sweated emotionally, the exhalation rate of organic substrates showed some variation, namely a higher of exhalation rate compared to the case of mostly due to insensible perspiration. Therefore, emotionally-induced sweating can enhance the release of organic substrates.
- 公益社団法人日本薬学会の論文
- 2002-07-01
著者
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TSUDA TAKAO
Department of Computer Engineering, Faculty of Information Sciences, Hiroshima City University
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INAI Yoshihito
Department of Thoracic and Cardiovascular Surgery, Hyogo College of Medicine
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Tsuda T
Department Of Applied Chemistry Faculty Of Engineering Nagoya Institute Of Technology
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Tsuda Takao
Department Of Anesthesiology Nagoya City University Medical School
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HIRABAYASHI Tadamichi
Department of Environmental Technology and Urban Planning Graduate School of Engineering, Nagoya Ins
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Inai Y
Department Of Environmental Technology And Urban Planning Graduate School Of Engineering Nagoya Inst
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Inai Yoshihito
Department Of Thoracic And Cardiovascular Surgery Hyogo College Of Medicine
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Inai Yoshihito
Department Of Environmental Technology And Urban Planning Graduate School Of Engineering Nagoya Inst
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Hirabayashi T
Department Of Environmental Technology And Urban Planning Graduate School Of Engineering Nagoya Inst
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Hirabayashi Tadamichi
Department Of Environmental Technology And Urban Planning Graduate School Of Engineering Nagoya Inst
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NAITOH Ken
Department of Environmental Technology Postgraduate School of Engineering, Nagoya Institute of Techn
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Naitoh Ken
Department Of Environmental Technology Postgraduate School Of Engineering Nagoya Institute Of Techno
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Inai Yoshihito
Department of Cardiology, Rakuwakai Otowa Hospital
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