Effects of Dietary Konjac Mannan on Serum and Liver Cholesterol Levels and Biliary Bile Acid Composition in Hamsters
スポンサーリンク
概要
- 論文の詳細を見る
We studied the effect of dietary konjac mannan on serum and liver cholesterol levels and biliary bile acid composition in hamsters. In hamsters fed a control diet supplemented with konjac mannan for 6 weeks, serum and liver cholesterol levels were decreased significantly compared to hamsters fed the control diet. Addition of konjac mannan to the cholesterol-enriched diet reduced the elevation of serum cholesterol caused by feeding cholesterol. However, the absorption of cholesterol from the intestine was not changed between the four groups. The increase in the proportion of chenodeoxycholic acid in biliary bile acids was significantly enhanced in the hamsters fed both cholesterol and konjac mannan compared to bamsters fed the control diet. The change of the bile acid composition may suggest that konjac mannan inhibits the intestinal absorption of bile acids.
- 公益社団法人日本薬学会の論文
著者
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KURAMOTO Taiju
Institute ofPharmaceutical Sciences, Hiroshima University, School ofMedicine
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HOSHITA Takahiko
Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University
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Kuramoto Taiju
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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SHIMIZU Hideki
Institute of Pharmaceutical Science, Hiroshima University School of Medicine
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YAMAUCHI Mie
Institute of Pharmaceutical Science, Hiroshima University School of Medicine
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KUBOTA Naomi
Institute of Pharmaceutical Science, Hiroshima University School of Medicine
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MATSUDA Misa
Institute of Pharmaceutical Science, Hiroshima University School of Medicine
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Kubota N
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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Matsuda Misa
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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Yamauchi Mie
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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Shimizu H
Hiroshima Univ. School Of Medicine Hiroshima Jpn
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Hoshita Takahiko
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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Shimizu Hideki
Institute Of Pharmaceutical Science Hiroshima University School Of Medicine
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KURAMOTO Taiju
Institute of Pharmaceutical Science, Hiroshima University School of Medicine
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