EXTRACELLULAR EXCITATORY JUNCTIONAL CURRENT AT THE CRAYFISH NEUROMUSCULAR JUNCTION
スポンサーリンク
概要
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The nature of the falling phase of the synaptic current was studied in more detail at the crayfish neuromuscular junction and fundamental data relating to focally recorded excitatory junctional potentials (e.j.p.s) was complemented. The decay of extracellular e.j.p.s at the crayfish neuromuscular junction was almost exponential. The decay time constant of extracellular e.j.p.s varied considerably from one e.j.p. to another, the mean of the decay time constant being about 1 ms at the normal resting potential at a bath temperature of 22℃. There was no detectable correlation between the decay time constant and the amplitude of extracellular e.j.p.s which were induced by a single stimulation of the excitatory axon. Prolonged application of glutamate hardly affected the decay time constant of extracellular e.j.p.s. The significance of the study on the crayfish neuromuscular system was discussed.
- 公益社団法人日本薬学会の論文
著者
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Ishida Michiko
The Tokyo Metropolitan Institute Of Medical Science
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SHINOZAKI HARUHIKO
The Tokyo Metropolitan Institute of Medical Science
関連論文
- EVALUATION OF EXCITATORY AND INHIBITORY ACTIONS OF GLUTAMATE RELATED COMPOUNDS
- QUISQUALATE ACTION ON THE CRAYFISH NEUROMUSCULAR JUNCTION
- PREVENTION OF DESENSITIZATION OF THE GLUTAMATE RECEPTOR ON THE CRAYFISH OPENER MUSCLE BY CONCANAVALINA
- EXTRACELLULAR EXCITATORY JUNCTIONAL CURRENT AT THE CRAYFISH NEUROMUSCULAR JUNCTION
- AN ATTEMPT AT AN ANALYSIS OF THE FACTORS DETERMINING THE TIME COURSE OF THE GLUTAMATE RESPONSE IN THE CRAYFISH NEUROMUSCULAR JUNCTION
- DEVELOPMENTAL PHARMACOLOGY OF SLOW AND FAST MUSCLES IN THE CHICK
- SYNTHESES OF NEW GLUTAMATE INHIBITORS
- Inhibitory actions of vecuronium bromide on acetylcholine and glutamate responses at the frog and crayfish neuromuscular junction.