Preparation of N'-[2-(5,6-Dimethylbenzothiazolyl)]-N-furfuryloxamide with Plant Growth Regulatory Activity
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概要
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The reaction of the N-furfuryloxamic acid sodium salt (12) with 1,1'-oxalyldiimidazole (ODI) yielded the imidazolide (13) as an intermediate, and this directly reacted with 2-aminothiazole derivatives (14) or 2-aminobenzothiazole derivatives (15) under essentially neutral conditions to afford the N'-[2-(substituted thiazolyl)]- or N'-[2(substituted benzothiazolyl)]-N-furfuryloxamides (6 or 7).The prepared compounds (6 and 7) were examined for plant growth regulatory activity in a seed germination assay. The examination resulted in the discovery of some new revelations that N'-[2-(5,6-dimethylbenzothiazlyl)]-N-furfuryloxamide (7c) at the concentration of 1.0×10^<-3>M completely inhibited the radicle growth of both rape and leek seedings.
- 2000-09-01
著者
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Kitagawa Tokujiro
Faculty Of Pharmaceutical Sciences And High Technology Research Center Kobe Gakuin University
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TSUTSUI Chinatsu
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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Tsutsui Chinatsu
Faculty Of Pharmaceutical Sciences And High Technology Research Center Kobe Gakuin University
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