Syntheses and Activities of Bioquinone Substances. II. Ubichromenol Phosphates and Related Compounds
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概要
- 論文の詳細を見る
The syntheses of ubichromenol phosphates (III, n=3,6 and 9) and related compounds are described. Their chromatographic and spectral data were given. Moreover, III (n=9) was hydrogenated to perhydroubichromenol phosphate (IV) which was also prepared through the two different ways starting from ubiquinone-(45) II (n=9). From the results of a preliminary study of III (n=9) on the mitochondrial respiration of rat liver, it was found that the succinate dehydrogenase activity was not affected, but both the succinate oxidase and the succinate-neotetrazolium chloride oxidoreductase activities were inhibited, and a marked difference from the effect of ubiquinone.
- 公益社団法人日本薬学会の論文
- 1971-08-25
著者
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赤 輝也
Research Laboratory, Taisho Pharmaceutical Co., Ltd.
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渡辺 慶昭
Research Center, Taisho Pharmaceutical Co., Ltd.,
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赤 輝也
Research Laboratory Taisho Pharmaceutical Co. Ltd.
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鈴木 正
Research Laboratory, Taisho Pharmaceutical Co., Ltd.
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渡辺 慶昭
Research Laboratory Taisho Pharmaceutical Co. Ltd.
-
鈴木 正
Research Laboratory Taisho Pharmaceutical Co. Ltd.
-
渡辺 慶昭
Research Center Taisho Pharmaceutical Co. Ltd.
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