Crystal Structures of Nadifloxacin Anhydride and Its Hemihydrate
スポンサーリンク
概要
- 論文の詳細を見る
The crystal structures of nadifloxacin [9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidyl)-5-methyl-1-oxo-1H, 5H-benzo[i, j]quinolizine-2-carboxylic acid, OPC-7251]anhydride and its hemihydrate were determined by X-ray analysis. In both crystals, two crystallographically independent molecules (A and B) are contained in an asymmetric unit. Two of molecule A and two of molecule B are tightly bound by hydrogen bonds around a center of symmetry. The structural features of nadifloxacin molecules in the two crystals are very similar to each other.
- 公益社団法人日本薬学会の論文
- 1994-04-15
著者
-
木戸 勝
Second Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
-
橋本 公司
Second Tokushima Institute of New Drug Research, Otsuka Pharmaceutical Co., Ltd.,
-
Kido Masaru
Second Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
-
橋本 公司
Second Tokushima Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
関連論文
- The Crystal Structures of 5-Hydroxy-3,4-dihydro-2-quinolone and 5-Hydroxy-1-methyl-3,4-dihydro-2-quinolone
- The Crystal Structures of 2-Quinolone and 8-Acetoxy-2-quinolone
- The Crystal Structure of Carteolol Hydrochloride : 5-(3-tert-Butylamino-2-hydroxy) propoxy-3,4-dihydro-2-quinolone, OPC-1085
- Synthetic Studies on Cephalotaxus Alkaloids. A Synthesis of (±)-Cephalotaxine
- A Convenient Synthesis of 1,3,4,5,-Tetrahydro-2H-3-benzazepin-2-ones by Acid-Catalyzed Cylization of N-(2-Arylethyl)-N-methyl-2-sulfinylacetamides
- Photochemistry of 2-(N-Acyl-N-alkylamino)cyclohex-2-enones : Formation of Spiro-β-lactams(Organic,Chemical)
- Synthesis of 2(1H)-Quinolinone Derivatives and Their Inhibitory Activity on the Release of 12(S)-Hydroxyeicosatetraenoic Acid (12-HETE) from Platelets
- 30 沖縄サンゴ礁生物Clavularia属軟サンゴ2種の成分研究
- Marine Natural Products. XII. On the Chemical Constituents of the Okinawan Marine Sponge Hymeniacidon aldis
- CLAVUKERIN A, A NEW TRINOR-GUAIANE SESQUITERPENE FROM THE OKINAWAN SOFT CORAL CLAVULARIA KOELLIKERI
- THREE NEW ent-VALERENANE SESQUITERPENES FROM AN OKINAWAN SOFT CORAL
- Absolute Structure of Ionol Glucoside : A Single-Crystal X-Ray Analysis of Dendranthemoside A Pentaacetate
- Conformation and Absolute Sterochemistry of Macrocalyxoformin D (=Longirabdiol)
- A Practical Synthesis of (S)-(-)-Nadifloxacin : Novel Acid-Catalyzed Racemization of Tetrahydroquinaldine Derivative
- Synthesis of 5-Fluorouracil Derivatives Containing an Inhibitor of 5-Fluorouracil Degradation
- Stichlorogenol and Dehydrostichlorogenol, Genuine Aglycones of Stichlorosides A_1,B_1,C_1 and A_2,B_2,C_2,from the Sea Cucumber Stichopus Chloronotus (BRANDT)
- Synthesis and Absolute Configuration of the Enantiomers of 7-Fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone (Flosequinan)
- The Absolute Configuration of (R)-(+)-Nadifloxacin
- Crystal Structures of Nadifloxacin Anhydride and Its Hemihydrate
- X-Ray Structures of Two Photodimers of 2-Methyl-1,4-naphthoquinone (Menadione)
- Intramolecular [2+2] Photocycloaddition of 2-[N-Acyl-N-(2-propenyl)-amino] cyclohex-2-enones : Synthesis of 2-Azabicyclo [2.1.1] hexanes
- INTRAMOLECULAR PHOTO [2+2] CYCLOADDITION OF 2-ALLYLOXY-AND 2-ALLYLAMINOCYCLOHEX-2-ENONES : FORMATION OF 2-OXA-AND 2-AZA-BICYCLO [2.1.1] HEXANE SYSTEMS
- Glochidionolactones A-F : Butenolide Glucosides from Leaves of Glochidion zeylanicum (GAERTN) A. JUSS
- A Novel Dimeric Butenolide, Glochidiolide, from the Leaves of Glochidion Acuminatum MUELL