Noval Method for the Synthesis of 2', 3'-Unsaturated Nucleosides from 2'(3')-Acetoxy-3'(2')-halogeno Derivatives by Using Sodium Dithionite with Viologen as a Reductive Elimination Mediator

スポンサーリンク

概要

• 論文の詳細を見る

• Reductive elimination of vicinal acetylated halohydrins with Na_2S_2O_4 as the reducing agent and viologen as the reduction mediator in a two-phase water-organic system is described. 2', 3'-Unsaturated nucleosides such as 1-(5-O-acetyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine, -hypoxanthine and uracil were obtained from 2'(3')-acetoxy-3'(2')-halogeno derivatives in good yields by meanes of this procedure.

• 公益社団法人日本薬学会の論文
• 1991-03-25

著者

• 網野 裕右

  Central Research Laboratories, Ajinomoto Co., Inc.,

• 網野 裕右

  Central Research Laboratories Ajinomoto Co. Inc.

• 岩上 寿夫

  Central Research Laboratories Ajinomoto Co. Inc.

関連論文

• Phenylalanine Derivatives Enhancing Intestinal Absorption of Insulin in Mice
• Synthesis of 1,5-Disubstituted Imidazoles Including an Imidazole Analogue of Prostaglandin from 4(5)-Hydroxymethylimidazole
• Noval Method for the Synthesis of 2', 3'-Unsaturated Nucleosides from 2'(3')-Acetoxy-3'(2')-halogeno Derivatives by Using Sodium Dithionite with Viologen as a Reductive Elimination Mediator

スポンサーリンク