Effect of Phenolic Acids and Related Compounds on Gastric Acid Secretion in the Rat
スポンサーリンク
概要
- 論文の詳細を見る
Response of gastric acid secretion to benzyloxycarbonyl-Trp-Met-Asp-Phe-NH_2 (tetragastrin) before and after perfusion of phenolic acids and related compounds was examined in the rat. Tannic acid and gallic acid inhibited the response to tetragastrin after perfusion of these compounds. But protocatechuic acid, p-hydroxybenzoic acid, salicylic acid, and aspirin stimulated the response to tetragastrin, and sometimes enhanced the basal acid secretion. Possible mechanism of ulcerative action of aspirin is discussed.
- 社団法人日本薬学会の論文
- 1978-01-25
著者
-
谷 覚
Faculty of Pharmaceutical Sciences, Josai University
-
谷 覚
Faculty Of Pharmaceutical Sciences Josai University
関連論文
- Pepsinogen Secretion from Cultured Rat Gastric Mucosal Cells
- Serum Pepsinogen Levels in Normal and Experimental Peptic Ulcer Rats Measured by Radioimmunoassay(Biological)
- Interaction among Secretagogues on Pepsinogen Secretion from Rat Gastric Chief Cells
- Secretion of Intrinsic Factor from Cultured Rat Gastric Chief Cells
- Inhibitory Action of Somatostatin on cAMP Dependent Pepsinogen Secretion from Rat Gastric Chief Cells : Involvement of Pertussis Toxin-Sensitive G-Protein
- Somatostatin Inhibits Pepsinogen Secretion without Influencing Cytosolic Free Ca^ Increase Induced by Carbachol and Cholecystokinin Octapeptide in Rat Chief Cells
- Direct Inhibition of Pepsinogen Secretion from Rat Gastric Chief Cells by Somatostatin
- Effect of Phenolic Acids and Related Compounds on Gastric Acid Secretion in the Rat