Suppressive Effect of Cycloheximide-p-chlorocinnamate on Immune Responses in Mice

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概要

• 論文の詳細を見る

• Effects of cycloheximide-p-chlorocinnamate on humoral and cellular immune response in mice were investigated. The compound i) suppressed primary and secondary hemagglutinin response, ii) inhibited preferentially the production of IgG type antibodies, iii) reduced the number of hemolytic plaque forming cells in the spleen to nearly zero, and iv) suppressed the induction of delayed-type skin hypersensitivity and foot pad reaction.

• 公益社団法人日本薬学会の論文
• 1977-01-25

著者

• 黒葛原 啓

  Pharmacological Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 黒葛原 啓

  R & D Planning Division Tanabe Seiyaku Co. Ltd.

• 荻原 和男

  Pharmacological Research Laboratory, Tanabe Seiyaku Co., Ltd.

• Tsuzurahara K

  R & D Planning Division Tanabe Seiyaku Co. Ltd.

• 荻原 和男

  Pharmacological Research Laboratory Tanabe Seiyaku Co. Ltd.

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• 4-Acylaminophenol Derivatives as Novel Lipoxygenase Inhibitors : Synthesis and Inhibitory Effect on 5-Lipoxygenase and Leukotriene B_4 Production
• Suppressive Effect of Cycloheximide-p-chlorocinnamate on Immune Responses in Mice
• Suppressive Effect of Cycloheximide Cinnamates on Immune Response and Tumor Growth in Mice-A Structure-activity Relationship with Respect to the Substituent on the Benzene Ring of the Cinnamic Acid Moiety

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