Studies on Pyrimidine Derivatives. III. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (3).

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概要

• 論文の詳細を見る

• The reduction product of 2-chloro-4-thiocyano-5-nitropyrimidine (I) was found to be 2-chloro-4-thiocyano-5-aminopyrimidine (II). Reaction of (II) with sodium ethoxide or ethanethioxide gave 2,4-diethoxy-5-aminopyrimidine and 2-ethylthio-4-thiocyano-5-amino-pyrimidine. 2-Chloro-4-mercapto-5-aminopyrimidine reacted with acetic anhydride and the resulting product was 2-methyl-5-chlorothiazolo [5,4-d] pyrimidine, the chlorine of which is reactive.

• 公益社団法人日本薬学会の論文
• 1958-08-15

著者

• 井上 昭二

  Pharmaceutical Faculty Nagoya City University

関連論文

• Studies on Pyrimidine Derivatives. VII. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (7)
• Studies on Pyrimidine Derivatives. VI. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (6).
• Studies on Pyrimidine Derivatives. V. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (5).
• Studies on Pyrimidine Derivatives. IV. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (4).
• Studies on Pyrimidine Derivatives. III. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (3).
• Studies on Pyrimidine Derivatives. II. Synthesis of Thiazolo [5,4-d] pyrimidines and Related Compounds. (2).
• Studies on Pyrimidine Derivatives. I. Synthesis of Thiazolo [5,4-d]-pyrimidines and Related Compounds. (1).

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