Biochemical Studies on Pathogenic Fungi. VII. The Effect of Synthetic Fungicides and Fatty Acids on the Respiration of Trichophyton gypseum.
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概要
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The effect of synthetic fungicides and fatty acids on the respiration of normal and pleomorphic forms of Trichophyton gypseum was examined manometrically. Organic thiomercuric fungicides, cationic detergents, and undecylenic acid markedly inhibited the respiration in as low as 10^<-3> to 10^<-5> molar concentration. Close relationship was observed between their respiration- and growth-inhibiting effects. The pleomorphic form was much more sensitive to the action of these compounds than the normal form of this fungus. Every saturated fatty acid of even-numbered series from C_2 to C_<16> stimulated the respiratory rate of this fungus in a certain range of concentrations, while higher members among them above C_8 inhibited it in relatively higher concentration. The inhibitory action was stronger in the undissociated state than as anion of the same acid, and was the maximum with the C_<12> acid. This dermatophyte was more sensitive to the action of these acids than bacterial species examined.
- 公益社団法人日本薬学会の論文
- 1957-12-20
著者
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藤井 達三
Department of Biochemistry, Gifu Prefectural Medical School
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藤井 達三
Department Of Biochemistry Gifu Prefectural Medical School
関連論文
- Biochemical Studies on Pathogenic Fungi. VI. Nutritional Studies on Trichophyton gypseum with Special Reference to its Pleomorphism.
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- Biochemical Studies on Pathogenic Fungi. VIII. The Effect of an Antibiotic, Trichomycin, on the Respiration and Phosphorus Metabolism of Trichophyton gypseum.
- Biochemical Studies on Pathogenic Fungi. VII. The Effect of Synthetic Fungicides and Fatty Acids on the Respiration of Trichophyton gypseum.
- 病原性糸状菌の生化学的研究(第4報)皮膚糸状菌の呼吸研究の為のSubmerged Culture