Synthesis and Hypolipidemic Activity of Diesters of Arylnaphthalene Lignan and Their Heteroaromatic Analogs

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概要

• 論文の詳細を見る

• A series of diesters of arylnaphthalene lignan and their heteroaromatic analogs were synthesized and evaluated for hypolipidemic activity. The diesters with modifications at C-3 showed excellent hypocholesterolemic and high-density lipoprotein (HDL) cholesterol-elevating activities. Structure-activity analysis indicated that the 2-pyridylmethyl ester 51 has the optimum activity.

• 公益社団法人日本薬学会の論文
• 1997-04-15

著者

• Ohtani Akio

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• Kondo K

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• Kondo Kazuhiko

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• TAKASHIMA Kohki

  Research Laboratories, Tanabe Seiyaku Co., Ltd.,

• KURODA Tooru

  Research Laboratories of Tanabe Seiyaku Co., Ltd.,

• IWASAKI Tameo

  Research Laboratories of Tanabe Seiyaku Co., Ltd.,

• Iwasaki T

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• Kuroda Tooru

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• Takashima K

  Research Laboratories Of Tanabe Seiyaku Co. Ltd.

• Takashima Kohki

  Research Laboratories Tanabe Seiyaku Co. Ltd.

• TAKASHIMA Kohki

  Research Laboratories of Tanabe Seiyaku Co., Ltd.,

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• Synthesis and Hypolipidemic Activity of Diesters of Arylnaphthalene Lignan and Their Heteroaromatic Analogs

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