The Influence of Ligand Side Chain on the Enantioselectivity of Lewis Acid Catalyzed Diels-Alder Reactions

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概要

• 論文の詳細を見る

• The enantioselective Lewis acid-catalyzed Diels-Alder reaction of 3-(2-propenoyl)-1,3-oxazolidin-2-one 8 with cyclopentadiene was examined using a series of chiral mox ligands 2-6, deferring in the side chain at 2-position of the chiral oxazoline and in the nature of the substituent at the chiral center (4-position) of the oxazoline ring, and a combination of N-[(1R)-2-chloro-1-phenylethyl]-2-[(4R)-4-phenyl-4,5-dihydrooxazol-2-yl]butyramide 2-Mgl_2-I_2 was the most efficient catalyst.

• 公益社団法人日本薬学会の論文
• 2002-09-01

著者

• Honda Y

  Faculty Of Pharmaceutical Sciences Josai University

• Honda Yuko

  Faculty Of Pharmaceutical Sciences Josai University

• Yamauchi Masashige

  Faculty of Pharmaceutical Science,Josai University

• ITAI Kazuhiro

  Faculty of Pharmaceutical Sciences, Josai University

• Itai Kazuhiro

  Faculty Of Pharmaceutical Sciences Josai University

• Yamauchi Masashige

  Faculty Of Pharmaceutical Science Josai University

• Yamauchi M

  Faculty Of Pharmaceutical Sciences Josai University

関連論文

• Diastereoselective synthesis of 2-alkylated 4-silyloxyprolineesters
• The Influence of Ligand Side Chain on the Enantioselectivity of Lewis Acid Catalyzed Diels-Alder Reactions
• Synthesis of 1-Hydroxybicyclo[3.2.1]oct-3-en-2-ones by Acyloin Rearrangement of 1-Methoxy- or 1-tert-Butyldimethylsilyloxy-bicyclo[2.2.2]oct-5-en-2-ones
• Reactivity of 2-Methylene-1, 3-dicarbonyl Compounds. 1, 3-Dipolar Cycloaddition Reaction with Ethyl Diazoacetate
• Base-promoted Acyloin Rearrangement of 1,8-Di-tert-butyldimethylsilyl-oxybicyclo[2.2.2]oct-5-en-2-ones
• Photochemical Synthesis of Bicyclo[4.1.0]hept-2-enes

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