New Cytotoxic Cardenolide Glycoside from the Seeds of Cerbera manghas
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概要
- 論文の詳細を見る
A new cytotoxic cardenolide glycoside, 3β-O-(2'-O-acetyl-α-L-thevetosyl)-14β-hydroxy-7-en-5β-card-20(22)-enolide, (7,8-dehydrocerberin), together with five known cardenolides, 17β-neriifolin, deacetyltanghinin, tanghinin, cerberin and 2'-O-acetyl-cerleaside A were isolated from the seeds of Cerbera manghas L. Their structures were elucidated by 1D- and 2D-NMR techniques as well as UV, IR and mass spectral data. 7,8-Dehydrocerberin, deacetyltanghinin and tanghinin exhibited cytotoxic activities against oral human epidermoid carcinoma (KB), human breast cancer cell (BC) and human small cells lung cancer (NCI-H187).
- 2004-08-01
著者
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KARALAI Chatchanok
Department of Chemistry, Faculty of Science, Prince of Songkla University
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PONGLIMANONT Chanita
Department of Chemistry, Faculty of Science, Prince of Songkla University
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Chantrapromma Kan
Inst. Of Res. And Dev. Walailak Univ.
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CHEENPRACHA Sarot
Department of Chemistry, Faculty of Science, Prince of Songkla University
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RAT-A-PA Yanisa
Department of Chemistry, Faculty of Science, Prince of Songkla University
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CHANTRAPROMMA Kan
Institute of Science, Walailak University
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Rat-a-pa Yanisa
Department Of Chemistry Faculty Of Science Prince Of Songkla University
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Chantrapromma Suchada
Crystal Materials Res. Unit Dep. Of Chemistry Fac. Of Sci. Prince Of Songkla Univ.
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Ponglimanont Chanita
Dep. Of Chemistry And Center Of Excellence For Innovation In Chemistry Fac. Of Sci. Prince Of Songkl
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Chantrapromma Kan
Institute of Research and Development, Walailak University
関連論文
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