Analysis of Aristolochic Acid I and II in Kampo Medicine Preparations
スポンサーリンク
概要
- 論文の詳細を見る
Herein reported are the detection methods of Aristolochic acid I (AA-I) and aristolochic acid II (AA-II), nephrotoxic components of the Aristolochia plants in Aristolochiaceae, in the Kampo medicine Toki-shigyaku-ka-goshuyu-shokyo-to. The confirmation of AA-I and AA-II was possible by the detection methods using a thin layer chromatography and a high performance liquid chromatography equipped with a Photodiode array detector (LC-PDA) and an electric ionization mass spectrometry detector. With the LC-PDA, it was possible to quickly detect AA-I and AA-II in the ten kinds of Kampo medicines in which the Aristolochia fangchi root or Aristolochia mandshuriensis stem may be misused. By using AA-I and AA-II purified from a commercial mixture by a preparative HPLC as reference standards, quantitative analyses of AA-I and AA-II were successfully carried out by use of the LC-PDA.
- 公益社団法人日本薬学会の論文
- 2002-10-01
著者
-
Seto Takako
Tokyo Metropolitan Institute Of Public Health
-
Seto Takako
Tokyo Metropolitan Research Laboratory Of Public Health
-
HAMANO Tomoko
Tokyo Metropolitan Research Laboratory of Public Health
-
Hamano T
Tokyo Metropolitan Research Laboratory Of Public Health
-
Kamimura Hisashi
Tokyo Metropolitan Research Laboratory Of Public Health
-
Shioda Hiroko
Tokyo Metropolitan Research Laboratory of Public Health
-
Seto Takako
Tokyo Metropolitan Inst. Of Public Health
-
HAMANO Tomoko
Tokyo Metropolitan Industrial Technology Research Institute
関連論文
- Analysis of Phenethylamines and Tryptamines in Designer Drugs Using Gas Chromatography-mass Spectrometry
- Inhibitory Effects of Shouseiryu-to on Two-Stage Carcinogenesis. II.Anti-tumor-promoting Activities of Lignans from Asiasarum heterotropoides var. mandshuricum
- Reaction of Malonaldehyde with Adenosine. Formation of a Novel Adduct Containing a Dioxazatricycloundecene Residue in the Base-pairing Region
- Analysis of Aristolochic Acid I and II in Kampo Medicine Preparations
- Performance of particleboard manufactured using air-injection press I : effects of air-injection press on preventing blowout of board manufactured from low-moisture particles
- Development of an air-injection press for preventing blowout of particleboard (III) : effects of pressing temperature on board performance
- Development of an air-injection press for preventing blowout of particleboard IV : effects of air-injection conditions on board performance and formaldehyde emission