Analysis of Phenethylamines and Tryptamines in Designer Drugs Using Gas Chromatography-mass Spectrometry
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概要
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We developed a method for determining the following ten psychedelic phenethylamines and tryptamines by gas chromatography-mass spectrometry (GC-MS). The phenethylamines examined were 3, 4, 5-trimethoxyamphetamine (TMA), 2, 4, 5-trime-thoxyamphetamine (TMA-2), 4-bromo-2, 5-dime-thoxyphenethylamine (2C-B), 4-iodo-2, 5-dimethoxy-phenethylamine (2C-I), 2, 5-dimethoxy-4-ethyl-thiophenethylamine (2CT-2), and 2, 5-dimethoxy-4-propylthiophenethylamine (2CT-7). The tryptamines examined were 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT), a-methyltryptamine (AMT), N-isopropyl-5-methoxy-N-methyltryptamine (5-MeO-MIPT), and N, N-diisopropyl-5-methoxytryptamine (5-MeO-DIPT). As the reference standards, five compounds were newly synthesized, and five were purified from the products. These were all structurally ascertained by GC-MS and nuclear magnetic resonance (NMR) spectroscopy. Between April 2005 and March 2007, 8 compounds analyzed in this study were found in 100 out of the 178 products which were examined.
- 2008-02-01
著者
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Yoshida Takemi
Showa Univ.
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Suzuki Jin
Tokyo Metropolitan Institute Of Public Health
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Seto Takako
Tokyo Metropolitan Institute Of Public Health
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Takahashi Misako
Tokyo Metropolitan Institute of Public Health
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Nagashima Machiko
Tokyo Metropolitan Institute of Public Health
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Yasuda Ichirou
Tokyo Metropolitan Institute of Public Health
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Yoshida Takemi
Showa University
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Seto Takako
Tokyo Metropolitan Inst. Of Public Health
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Suzuki Jin
Tokyo Metropolitan Inst. Of Public Health
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