Potentiation of Cytotoxic Activity in Naive and Tumor-Bearing Mice by Oral Administration of Hot-Water Extracts from Agaricus brazei Fruiting Bodies (Miscellaneous)
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概要
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When hot-water extracts of mushroom Agaricus brazei MURRILL fruiting bodies (Agaricus extracts) were administered orally into Meth A-bearing mice, tumor growth was significantly inhibited compared with controls given water orally. Treatment with Agaricus extracts for five successive days significantly increased natural killer activity of spleen cells in naive BALB/c mice. In Meth A-bearing BALB/c mice, Agaricus extracts enhanced the induction of antigen-specific cytotoxic T lymphocytes and interferon γ production, indicating that Agaricus extracts potentiate cytotoxic activity in innate and adaptive immunity.
- 公益社団法人日本薬学会の論文
- 2004-03-01
著者
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KAWAGUCHI Kiichiro
Medicinal Plant Garden, School of Pharmaceutical Sciences, Kitasato University
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Takimoto Hiroaki
Denartment Of Biosciences School Of Science Kitasato University
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WAKITA Daiko
Denartment of Biosciences, School of Science, Kitasato University
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KUMAZAWA Yoshio
Denartment of Biosciences, School of Science, Kitasato University
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Wakita Daiko
Denartment Of Biosciences School Of Science Kitasato University
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Kumazawa Yoshio
Denartment Of Biosciences School Of Science Kitasato University
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Kawaguchi Kiichiro
Medicinal Plant Garden School Of Pharmaceutical Sciences Kitasato University
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Kawaguchi Kiichiro
Medicinal Plant Garden School Of Pharmaceutical Science Kitasato University
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