Clinical Study of Cerebrospinal Fluid Dynamics Using ^<111>In-DTPA SPECT in Patients With Subarachnoid Hemorrhage
スポンサーリンク
概要
- 論文の詳細を見る
The ventricle-to-background ratio and clearance rate constant measured by indium-111 diethylenetriaminepenta-acetic acid single photon emission computed tomography (^<111>In-DTPA SPECT) were evaluated for predicting hydrocephalus in 16 patients at 2 to 3 weeks after onset of subarachnoid hemorrhage. The activity in the lateral ventricles, basal cistern, and hemispheric convexities was measured at 6, 24, and 48 hours after lumbar injection of radionuclide. In the follow-up study, eight patients developed hydrocephalus, and required ventriculoperitoneal shunting. Radioactivity measured in the hemispheric convexity did not reach peak activity within 48 hours. The clearance rate measured by applying the mono-exponential equation failed to show delayed clearance of radionuclide in hydrocephalus. The ratio between the ventricle and basal cistern measured at 6 hours postinjection was the best predictor of hydrocephalus (F(1, 30)=42.84, p<0.0001). These results suggest that a single ^<111>In-DTPA SPECT scan may be sufficient to identify patients at risk of developing hydrocephalus.
- 日本脳神経外科学会の論文
- 2006-01-15
著者
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ISHIKAWA Tatsuya
Department of Surgical Neurology, Research Institute for Brain and Blood Vessels-Akita
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KAMIYAMA Hiroyasu
Department of Neurosurgery, Asahikawa Red Cross Hospital
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NAKAMURA Toshitaka
Department of Orthopedic Surgery, University of Occupational and Environmental Health
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Kazumata Ken
Department Of Neurosurgery Teine Keijinkai Hospital
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MAKINO Kenichi
Department of Neurosurgery, Asahikawa Red Cross Hospital
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TAKIZAWA Katsumi
Department of Neurosurgery, Asahikawa Red Cross Hospital
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KOMEICHI Takahiro
Department of Neurosurgery, Asahikawa Red Cross Hospital
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KUBOTA Takamichi
Department of Neurosurgery, Asahikawa Red Cross Hospital
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MAKINO Kennichi
Department of Neurosurgery, Asahikawa Red Cross Hospital
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Ishikawa Tatsuya
Department Of Surgical Neurology Research Institute For Brain And Blood Vessels-akita
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Makino Kennichi
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Makino Kenichi
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Nakamura Toshitaka
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Ishikawa Tatsuya
Department Of Neonatology And Pediatrics Nagoya City University Graduate School Of Medical Sciences
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Kamiyama Hiroyasu
Department Of Neurosurgery Asahikawa Red-cross Hospital
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Kamiyama Hiroyasu
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Kubota Takamichi
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Ishikawa Tatsuya
Department Of Civil Engineering Nagoya University
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Takizawa Katsumi
Department Of Neurosurgery Asahikawa Red-cross Hospital
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Komeichi Takahiro
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Ishikawa Tatsuya
Department Of Neurosurgery Hokkaido University School Of Medicine
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Ishikawa Tatsuya
Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo
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Kamiyama Hiroyasu
Department Of Neurosurgery Asahiakawa Red Cross Hospital
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Takizawa Katsumi
Department Of Neurosurgery Asahikawa Red Cross Hospital
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Takizawa Katsumi
Department of Chemistry, Faculty of Science, Shinshu University
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