シヨウジヨウバエ腫瘍の組織培養 : III.メラニン性腫瘍に及ぼすCuイオンの影響
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概要
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1. The melanotic tumors in the hind-intestines of the mature third-instar larvae of v tu and st tu strains of D. melanogaster were cultured in the synthetic medium involving 1mM, 2.5mM, and 5mM CuSO_4・5H_2O respectively, to investigate the effects of Cu-ion upon the melanotic growth. 2. When 1mM CuSO_4・5H_2O was added in the synthetic medium, the melanotic growth was observed to be inhibited markedly. The addition of 2.5mM CuSO_4・5H_2O to the synthetic medium showed no significant difference from culturing without CuSO_4・5H_2O. 5mM CuSO_4・5H_2O involved in the synthetic medium showed the effect of accelerating the melanotic growth pronouncedly. 3. As a result of the above facts, the presence of the substance inhibiting phenol oxidase system was assumed in the process of melanine formation, and this inhibitory substance might be accelerated by 1mM CuSO_4・5H_2O.
- 社団法人日本動物学会の論文
- 1956-08-15
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