甲状腺の初期分化について

概要

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MARCUS (1933) suggested that the thyroid, which, according to him is ectodermal in origin, is dependent for its full differentiation upon contact with the endoderm of the fore-gut. Experiments reported by the writer ('39, '40) in previous papers showed that the thyroid was of endodermal origin, so I disagreed with MARCUS about the origen of the thyroid. The present investigation was attempted to analyse in Triturus pyrrhogaster the necessary condition for the differentiation of the organ. I transplanted pieces of somites to the cardiac region (Fig. 1, a) or to the antero-lateral regions of the trunk (Fig. 1, b). In the former trial the results were uncertain, while in the latter I obtained 4 successful cases, in which thyroid failed to develop in 3 cases. It seems probable that contact of the heart anlage with the endodermal fore-gut floor provides necessary conditions for thyroid differentiation.
社団法人日本動物学会の論文
1941-06-15