Functions and Properties of Animal Lectins
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概要
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A variety of animal lectins have been isolated and characterized by extensive studies during a century after the discovery of a lectin in 1888. Animal lectins distribute in a variety of locations of the body and perform a variety of roles. However, it is still difficult to determine endogenous functions of lectins since their structures both of the primary amino acid sequence and of the tertiary structure detected immunologically were alike each other among several lectins, and endogenous ligands were obscure. This review describes animal lectins whose functions are relatively apparent. Agglutination of erythrocytes and/or glycoproteins has bcen an important factor for the definition of a lectin so far, representing the existence of two sugar-binding sites. Since the discovery of sugar-binding proteins which have a single binding site, it is claimed to build a new definition to reconcile all sugar-binding proteins under the term lectin.
- 社団法人日本動物学会の論文
- 1990-08-15
著者
関連論文
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