わが国におけるドナープラズマフェレーシスの現状

概要

論文の詳細を見る
In 1986, donor plasmapheresis (DPP) was introduced into Japanese Red Cross Blood Services (JRCBS) in order to procure fresh plasma for the national self-sufficiency of blood coagulation factor VIII (Fc VIII). According to the national policy, JRCBS has promoted DPP such as platelet poor plasma of platelet rich plasma collection using centrifugal devices (Haemonetics PCS) or membrane devices (Asahimedical APC-4000). As a result, the number of DPP has averaged over 1,200,000 per year, and enabled us to procure 100% of the source plasma for Fc VIII. On the other hand, clinical demands of 5-unit FFP (fresh frozen plasma) is increasing year by year, and the number of 5-unlt FFP supplied per year has been over 100,000. Recently, recombinant Fc VIII has been successfully applied and the clinical use of recombinant albumin is prospected in the near future. Therefore, the purpose of DPP is surmised to be a shift from the standpoints of securing source plasma to clinical demands of 5-unit FFP.
日本アフェレシス学会の論文
1998-02-28