ENDOCYTIC MECHANISM OF MACROPHAGES TO ANIONIC FOREIGN SUBSTANCES
スポンサーリンク
概要
- 論文の詳細を見る
To study the non-immunogenic defense mechanism on organisms against foreign substances, reactions of cells to anionic colloidal particles were observed on macrophages from rat peritoneal cavity and liver tissues. As the non-antigenic anionic particles, iron colloids obtained by coating ferric hydroxide colloidal particles with potassium polyvinyl sulfate or chondroitin sulfate were used. Observations revealed that peritoneal macrophages and Kupffer cells develop surface receptors having specific affinity to anionic particles by which the cells adsorb them on the surface and internalize them into the cytoplasm for decomposition or detoxication. The other general somatic cells did not have any such receptors and were unable to take up the foreign particles having a negative surface charge.
- 日本組織細胞化学会の論文
著者
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ONO Toshiro
Department of Immunology, Okayama University Graduate School of Medicine and Dentistry
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Ono Toshiro
岡山大学 歯 口腔病理
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Awai M
Department Of Pathology Okayama University Medical School
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Awai Michiyasu
Department Of Pathology Okayama University Medical School
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Ono Toshiro
Department Of Immunology Okayama University Graduate School Of Medicine And Dentistry
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Ono Toshiro
Department of Chemistry, Faculty of Science, Okayama University
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