睾丸腫瘍の免疫学的研究 : マウス可移植性腹水型睾丸間質細胞腫に対する担癌宿主の体液性抗腫瘍抗体産生

概要

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An estrogen-induced testicular interstitial cell tumor (TICT), originated in an A strain mouse testis and maintained in A/St mice, was converted into an ascitic form in A/St mice in our laboratory. The humoral antibody response to the ascitic TICT in ascitic TICT-bearing mice was demonstrated by sensitive immune adherence reaction. The antibody reactive transplantation antigen on the ascitic TICT was indicated to be tumor specific. The antibody response of the tumor-bearing hosts was maximum at their terminal stage of tumor-bearing state and it was even higher than that of the mice which had been immunized subcutaneously with ^<60>Co irradiated ascitic TICT cells and resisted against an intraperitoneal transplantation of nontreated tumor cells. The significance of these results was discussed.
社団法人日本泌尿器科学会の論文
1975-10-20