大網膜および大網膜と金箔併用による膀胱補填に関する実験的研究

概要

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The defect of the bladder wall of 2 cm in diameter was formed surgically in 40 rabbits of around 2.5 kg body weight. This defect was covered either by omentum or by combination of omentum and gold leaf. These rabbits were killed 2 days, one, two or four weeks after the operation and the bladder walls were observed histologically. The results were as follows: 1) The regeneration of the defect of the bladder wall was slightly postponed in the group with combination in comparison with the group with omentum alone. 2) Such phenomena seemed to depend upon the gold leaf as a foreign body which was apt to interrupt the regeneration of the mucous membrane and become the nucleus of the urinary bladder stone. 3) The strong reactions of urine infiltration were hardly found in the group with the combination of gold leaf and omentum compared with those in the group with omentum alone. 4) These results seemed to suggest some foreign body reactions to gold leaf, and slight infiltration of the urine by omentum. The former was concluded from the fact that the gold leaf was included completely within the regenerated tissue in some rabbits. Conclusion The results of these experiments suggest that the gold leaf will be a good material to substitute for the defect of bladder wall, if its size and thickness and the technique of operation are more examined in future studies.
社団法人日本泌尿器科学会の論文
1972-07-20