転移からみた腎癌の臨床成績について

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Analyzing three records : own cases, reports from 35 institutes and autopsized cases collected from the Annual of Pathological Autopsy Cases in Japan, the clinical results of renal carcinoma which were estimated from the survival rate of patients after treatment, were studied from the view-point of metastases. 1) Summarization from 35 institutes : 415 cases of renal carcinoma (221 mortal, 194 alive) were reported. Mortal cases with metastases were so many as 2.7 times the cases without them. Reviewing the survival rate of the groups divided into four terms (within 6 months, over 1, 2 and 5 years), it was found that the rate of cases without metastases was always higher than the cases with them. In the cases within 6 months of survival periods, each survival rate of the cases with metastasis and without them was 49.6 per cent and 64.7 per cent, but 3 years after treatment, the rate was 9.3 per cent and 11.8 per cent respectively. Even in cases with metastases, nephrectomy might elongate the life of the patients. While the patients with multiorganic metastases mostly die in one year, those with uniorganic metastases survived longer. For the period less than one year after treatment, radio therapy and anticarcinogenic agents made the survival rate higher to some degree, but no effect was noticed for longer years after-treatment. 2) Own cases : 28 cases of renal carcinoma were obtained from 1953 up to August of 1967. Six cases of them were alive for over 5 years after nephrectomy, two cases of which had metastases. The one that had metastases in the pericaval lymph-nodes already at the time of operation, and metastatic nodes in the lung was noticed to be alive 7 years after surgery. 3) Autopsied cases collected from the Annual of the Pathological Autopsy Cases in Japan : As to the site of metastases, lung and lymph-nodes were of highest incidence. Bone, liver and adrenal glands were of second frequency. The number of metastatic organs had mostly no influence upon the mortality rate of the patients. It is worth of warning that not a few number of metastases of the lung, bone etc, which can easily be detected clinically, had been overlooked.
社団法人日本泌尿器科学会の論文

転移からみた腎癌の臨床成績について

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