排尿機構にかんする検討 : 第5報いわゆる膀胱頚部硬化症の検討. 膀胱頚部組織における交感神経線維の分布について (組織蛍光法による検討)

概要

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Previously we reported on urinary flow rates, urethral pressure profiles and their responses to α-adrenergic blocking agent (phentolamine 5 mg iv) in patients who were urodynamically diagnosed as bladder neck contracture. It was found there were some responders to α-adrenergic blocking agent in these patients. In responders, urinary flow rates were remarkably improved and maximum urethral closure pressures were more significantly decreased after intravenous administration of Phentolamine (5mg). These results suggested us that the sympathetic nervous system or posterior urethra had important roles in the causation or bladder neck contracture. In this study, with the use or histochemical fluorescent technique (Falck-Hillarp's method), we examined the distribution of adrenergic neurons and its terminals in the bladder neck tissues which were transurethrally resected.
社団法人日本泌尿器科学会の論文