上部尿路機能に関する研究 : 第11報酸素電極法でみた腎自家移植前後の腎微小循環動態

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Although there have been a variety of methods for evaluation of functional states of the transplanted kidney, no direct method for measuring intrarenal microcirculation has been so far available. The purpose of this study was to determine if a polarographic measurement of intrarenal oxygen tension is useful for a rapid assessment of functional states of the autotransplanted kidney. The experiments were performed on 25 mongrel dogs, weigbing 8.5 to 32kg. After iv Thiamylal-Na administration, the kidney and ureter were exposed through a midline incision. Copper electrodes (a diameter of 300μ) were inserted into the renal cortex and medulla to the depth of 5mm and 15mm, respectively and tissue oxygen tensions were measured by the Yagi's polarographic method. The kidney was perfused immediately after nephrectomy and the renal artery was anastomosed to the right femoral artery and the renal vein to the right femoral vein. After the anastomosis was established, the renal PO_2 was monitored for 1 hr.
社団法人日本泌尿器科学会の論文