前立腺癌における酸性フォスファターゼの研究 : 第4報前立腺酸性フォスファターゼの免疫化学的測定

概要

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Prostatic acid phosphatase (PAP) activities were determined by counter immunoelectrophoresis (CIEP) and immunochemical assay using anti-PAP rabbit serum in blood and bone marrow sera of 20 patients with prostatic cancer (PC), 3 patients with benign prostatic hypertrophy (BPH), and 52 normal males and females. 1. PAP activity more than 0.55 to 1.1 Sigma unit/ml was detected as positive in CIEP. The positive results of CIEP in sera of patients with PC were as follows: none out of 3 patients (0%)with stage B (1 untreated and 2 treated), 1 out of 8 patients (12.5%) with stage C treated, 3 out of 4 patients (75.0%) with stage D untreated and 1 out of 5 patients (20.0%) with stage D treated. In bone marrow sera the positive rates were similar to rates in blood sera except stage D treated (0%). CIEP was negative in normal and BPH cases.
社団法人日本泌尿器科学会の論文